FOLIC ACID
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Folic Acid
Pharmaceutical Grade & Food Grade Folic Acid – Premium Quality Vitamin B9 for Pharmaceutical Formulations, Food Fortification & Dietary Supplement Manufacturing
Folic Acid is a vital B-complex vitamin extensively utilized in pharmaceutical manufacturing, food fortification, dietary supplement production, and animal feed applications. Our technical-grade folic acid delivers exceptional bioavailability and nutritional performance with superior purity for demanding pharmaceutical formulations, food enrichment programs, and nutraceutical applications requiring safe, effective folate supplementation.
✅ High-Performance Vitamin B9 – Superior Bioavailability & Nutritional Performance
✅ Multiple Grade Formulations – USP, BP, EP & Food Grade Specifications
✅ Essential Nutrient Properties – Neural Tube Defect Prevention & Cardiovascular Support
✅ Safe for Human Consumption – FDA Approved & Internationally Recognized Standards
✅ Pharmaceutical, Food Fortification, Dietary Supplements & Animal Feed Applications
Description
High-Performance Folic Acid for Pharmaceutical Manufacturing & Food Fortification Operations
Folic Acid represents essential vitamin technology specifically formulated for pharmaceutical manufacturing operations, food fortification programs, dietary supplement production, and animal nutrition applications requiring consistent folate delivery and bioavailability. This crucial B-complex vitamin serves critical functions across pharmaceutical formulations, food enrichment procedures, nutraceutical manufacturing, and industrial processes requiring controlled folate supplementation and nutritional enhancement.
At Chemicals & Process Equipment Limited, we supply high-grade Folic Acid manufactured under stringent quality control standards and international pharmaceutical specifications. Our comprehensive product range includes USP-grade, BP-grade, EP-grade, and food-grade formulations meeting diverse requirements for pharmaceutical manufacturing, food fortification, and specialized applications across global pharmaceutical, food, and nutraceutical markets.
✅ Advanced Vitamin Technology – Optimized Bioavailability & Nutritional Performance
✅ Consistent Quality Standards – Multiple Grade Classifications with Comprehensive Documentation
✅ Essential Health Properties – Neural Development & Cardiovascular Function Support
✅ Multi-Industry Applications – Pharmaceutical, Food Fortification, Supplements & Animal Feed Uses
✅ Technical Support Package – Complete Application Guidance & Process Optimization
For comprehensive information on folic acid applications in pharmaceutical manufacturing and food fortification, refer to this detailed folic acid and folate nutrition guide by ScienceDirect. Our pharmaceutical ingredients and vitamin compounds portfolio provides specialized guidance for optimal folate supplementation performance and formulation development across diverse pharmaceutical applications.
Folic Acid Market size was valued at USD 0.76 Billion in 2024 and the total Folic Acid revenue is expected to grow at a CAGR of 4.3%, while the Global Folic Acid market is poised to reach a value of USD 627.5 million in 2024, and further expand at a CAGR of 4.8% to reach USD 1,233.2 million by the year 2034. This growth is driven by increasing awareness of folate health benefits, mandatory food fortification programs, expanding pharmaceutical applications, and growing demand for prenatal nutrition across global healthcare markets.
Technical Specifications & Folic Acid Properties
| Property | USP Grade | BP Grade | EP Grade | Food Grade |
|---|---|---|---|---|
| Chemical Formula | C19H19N7O6 | C19H19N7O6 | C19H19N7O6 | C19H19N7O6 |
| Molecular Weight | 441.40 g/mol | 441.40 g/mol | 441.40 g/mol | 441.40 g/mol |
| Assay (Dried Basis) | 96.0-102.0% | 96.0-102.0% | 96.0-102.0% | 95.0-102.0% |
| Loss on Drying | ≤8.5% | ≤8.5% | ≤8.5% | ≤10.0% |
| Sulfated Ash | ≤0.3% | ≤0.3% | ≤0.3% | ≤0.5% |
| Related Substances | ≤2.0% total | ≤2.0% total | ≤2.0% total | ≤3.0% total |
| Heavy Metals (Pb) | ≤10 ppm | ≤10 ppm | ≤10 ppm | ≤20 ppm |
| Arsenic (As) | ≤3 ppm | ≤3 ppm | ≤3 ppm | ≤5 ppm |
| Mercury (Hg) | ≤1 ppm | ≤1 ppm | ≤1 ppm | ≤2 ppm |
| Cadmium (Cd) | ≤1 ppm | ≤1 ppm | ≤1 ppm | ≤2 ppm |
| Total Plate Count | ≤1000 cfu/g | ≤1000 cfu/g | ≤1000 cfu/g | ≤3000 cfu/g |
| Yeast & Mold | ≤100 cfu/g | ≤100 cfu/g | ≤100 cfu/g | ≤300 cfu/g |
| E.Coli | Absent/g | Absent/g | Absent/g | Absent/g |
| Salmonella | Absent/10g | Absent/10g | Absent/10g | Absent/10g |
| Appearance | Orange to yellow crystalline powder | Orange to yellow crystalline powder | Orange to yellow crystalline powder | Orange to yellow powder |
| Solubility | Slightly soluble in water | Slightly soluble in water | Slightly soluble in water | Slightly soluble in water |
| pH (1% solution) | 4.0-4.8 | 4.0-4.8 | 4.0-4.8 | 4.0-5.0 |
| Particle Size | 80-120 mesh | 80-120 mesh | 80-120 mesh | 60-100 mesh |
| Bulk Density | 0.4-0.6 g/mL | 0.4-0.6 g/mL | 0.4-0.6 g/mL | 0.3-0.5 g/mL |
| Storage Temperature | 2-8°C | 2-8°C | 2-8°C | Room temperature |
| Packaging Options | 1kg, 5kg, 25kg containers, controlled atmosphere |
Available Grade Types:
- USP grade folic acid for pharmaceutical formulations
- BP grade folic acid meeting British Pharmacopoeia standards
- EP grade folic acid for European pharmaceutical applications
- Food grade folic acid for fortification programs
- Feed grade folic acid for animal nutrition applications
Specialized Packaging Solutions:
- 1kg amber glass bottles with nitrogen flushing
- 5kg aluminum containers with desiccant protection
- 25kg fiber drums with moisture barrier lining
- Controlled atmosphere packaging for stability
- Cold chain storage and transportation systems
- Light-protected packaging for photostability
Pharmaceutical Applications
Prenatal Vitamin Formulations The Pharmaceuticals sector, valued at 0.18 USD Billion in 2023, focuses on folic acid’s therapeutic properties, especially in preventing birth defects. Pharmaceutical manufacturers utilize folic acid for prenatal vitamins, pregnancy supplements, and maternal health formulations requiring neural tube defect prevention and fetal development support.
Anemia Treatment Medications Pharmaceutical companies employ folic acid for treating megaloblastic anemia, folate deficiency disorders, and hematological conditions requiring folate repletion therapy.
Cardiovascular Health Formulations Folic acid is associated with various health benefits in the nutritional industry. It is known to support cardiovascular health by assisting in the breakdown of homocysteine, an amino acid associated with an increased risk of heart disease. Pharmaceutical operations use folic acid for cardiovascular health supplements, homocysteine reduction formulations, and heart health medications.
Neurological Support Medications Medical manufacturers employ folic acid in neurological support formulations, cognitive health supplements, and neuropsychiatric medications requiring folate cofactor support.
Food Fortification Applications
Cereal & Grain Fortification It is mainly used to fortify cereals/grains and dietary supplements. Food manufacturers utilize folic acid for enriching breakfast cereals, bread products, pasta, and grain-based foods meeting mandatory fortification requirements and public health initiatives.
Flour Enrichment Programs Food processors employ folic acid for wheat flour fortification, baking flour enhancement, and staple food enrichment programs supporting population-wide folate intake improvement.
Infant Formula Applications Infant nutrition manufacturers use folic acid for baby formula formulations, infant cereals, and pediatric nutrition products requiring optimal folate content for early development.
Functional Food Development Food companies employ folic acid for creating functional foods, fortified beverages, and health-oriented food products targeting specific nutritional needs.
Dietary Supplement Manufacturing
Multivitamin Formulations Nutraceutical manufacturers utilize folic acid for multivitamin tablets, softgel capsules, and comprehensive vitamin formulations requiring standardized folate content and bioavailability.
B-Complex Supplements Supplement companies employ folic acid for B-complex vitamins, energy formulations, and specialty vitamin products targeting metabolic support and energy production.
Prenatal Supplement Production Women’s health supplement manufacturers use folic acid for prenatal vitamins, pregnancy support formulations, and maternal nutrition products requiring optimal folate levels.
Senior Nutrition Supplements Geriatric nutrition companies employ folic acid for senior-specific supplements, memory support formulations, and age-related health products requiring cognitive and cardiovascular support.
Animal Feed & Veterinary Applications
Poultry Feed Fortification Animal nutrition companies utilize folic acid for poultry feed supplements, broiler nutrition programs, and egg production enhancement requiring optimal reproductive performance and health.
Swine Nutrition Programs Livestock feed manufacturers employ folic acid for pig feed formulations, sow reproductive nutrition, and swine growth enhancement applications requiring improved feed conversion and health.
Aquaculture Feed Applications Fish feed producers use folic acid for aquaculture nutrition, fish health supplements, and specialty aquatic feed formulations requiring optimal growth and disease resistance.
Pet Food Enhancement Companion animal nutrition companies employ folic acid for premium pet foods, veterinary therapeutic diets, and specialty animal nutrition products requiring enhanced nutritional profiles.
Clinical Nutrition Applications
Enteral Nutrition Formulations Medical nutrition manufacturers utilize folic acid for tube feeding formulations, liquid nutrition products, and clinical nutrition applications requiring complete vitamin profiles.
Parenteral Nutrition Solutions Hospital nutrition services employ folic acid for IV nutrition formulations, total parenteral nutrition, and specialized medical nutrition requiring controlled folate delivery.
Renal Nutrition Products Kidney disease nutrition companies use folic acid for dialysis patient supplements, renal-specific formulations, and chronic kidney disease nutrition support.
Cancer Nutrition Support Oncology nutrition manufacturers employ folic acid for cancer patient supplements, chemotherapy support formulations, and specialized cancer nutrition products.
Cosmetic & Personal Care Applications
Hair Care Formulations Cosmetic companies utilize folic acid for hair growth supplements, scalp health products, and hair strengthening formulations requiring follicle nutrition support.
Skin Health Products Personal care manufacturers employ folic acid for anti-aging supplements, skin nutrition formulations, and beauty supplements targeting cellular regeneration.
Nail Health Applications Beauty companies use folic acid for nail strengthening supplements, nail health formulations, and cosmetic nutrition products requiring keratin support.
Quality Control & Testing Procedures
Comprehensive Quality Assurance Every production batch undergoes extensive testing to ensure compliance with pharmaceutical and food safety specifications. Our quality control laboratory employs advanced analytical techniques including HPLC analysis, UV spectrophotometry, and microbiological testing.
Quality assurance procedures include:
- Assay determination via HPLC and UV spectrophotometric analysis
- Related substances testing using chromatographic methods
- Loss on drying measurement using gravimetric methods
- Heavy metals testing using ICP-MS procedures
- Microbiological testing including total plate count and pathogen screening
- Sulfated ash content analysis through controlled incineration
- Dissolution testing for pharmaceutical applications
- Particle size distribution analysis using sieve methods
- pH measurement of aqueous solutions
- Stability testing under accelerated and real-time conditions
Application Guidelines & Best Practices
Formulation Optimization Develop standardized formulation procedures based on therapeutic requirements, bioavailability needs, and stability considerations to ensure optimal folate delivery and product performance.
Stability Considerations Implement proper stabilization techniques including light protection, moisture control, and antioxidant systems to maintain folic acid potency throughout product shelf life.
Bioavailability Enhancement Establish formulation strategies for improving folic acid bioavailability including particle size optimization, solubility enhancement, and synergistic ingredient combinations.
Market Applications & Industry Trends
Government Fortification Mandates Sales of Folic Acid increased at 3.7% CAGR between 2019 and 2023. The USA is projected to hold a revenue share of 26.1% over the forecast period. China holds a 17.3% share of the global market for Folic Acid. Mandatory food fortification programs worldwide drive continued demand for folic acid in staple food applications.
Prenatal Health Awareness Folic acid supplements consumed before and during pregnancy may reduce the risk of heart defects in infants. Growing awareness of pregnancy nutrition and birth defect prevention supports expanding folic acid supplement market.
Aging Population Demographics Increasing elderly population and age-related health concerns drive demand for folic acid supplements targeting cardiovascular health and cognitive function support.
Environmental & Regulatory Compliance
FDA & International Standards The quality meets the standards of USP/BP/EP. Our folic acid products comply with FDA, USP, BP, EP, and international pharmaceutical standards, ensuring regulatory acceptance for pharmaceutical and food applications across global markets.
Good Manufacturing Practices Production facilities maintain cGMP compliance for pharmaceutical applications, ensuring quality consistency and regulatory compliance for medical and nutritional uses.
Food Safety Certification Food grade folic acid meets HACCP, BRC, and international food safety standards for fortification and nutritional enhancement applications.
Performance Advantages & Technical Benefits
✔ Superior Bioavailability – Enhanced folate absorption and therapeutic effectiveness
✔ Multiple Grade Options – USP, BP, EP, and food grade specifications for diverse applications
✔ Essential Health Benefits – Neural tube defect prevention and cardiovascular support
✔ Regulatory Compliance – Meeting international pharmaceutical and food safety standards
✔ Stability Performance – Optimized formulations for extended shelf life and potency retention
✔ Quality Consistency – Reliable performance with comprehensive analytical documentation
✔ Technical Expertise – Complete formulation support and application guidance
Our Folic Acid products represent industry-leading standards in vitamin technology and nutritional solutions, specifically formulated for demanding pharmaceutical manufacturing operations, food fortification procedures, and dietary supplement applications. We provide comprehensive technical support, formulation guidance, and regulatory consultation to ensure optimal performance across your specialized pharmaceutical manufacturing, food fortification, or nutraceutical production applications.
For detailed specifications, certificates of analysis, or application-specific recommendations, contact our specialized pharmaceutical ingredients division. We offer complete support including formulation development, stability testing, and regulatory guidance to maximize effectiveness in your pharmaceutical manufacturing, food fortification, or dietary supplement production applications.
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